- Salvation Army, Wrangell
- Satellite TV Service, Wrangell
- Savings Banks, Wrangell
- Sawmill & Planing Mills, Wrangell
- Sawmill Supplies & Equipment Repair, Wrangell
- Screen Printing, Wrangell
- Secondary Schools, Wrangell
- Senior Citizens Housing, Wrangell
- Sewing & Yarn Stores & Supplies, Wrangell
- Ship & Boat Building & Repairing, Wrangell
- Shopping & Shopping Services, Wrangell
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- Sightseeing Tours, Wrangell
- Social Services & Welfare, Wrangell
- Specialty Stores, Wrangell
- Staffing & Support Services, Wrangell
- State Government, Wrangell
- Steamship Companies & Agencies, Wrangell
- Stevedoring Contractors, Wrangell
- Surplus & Salvage Merchandise, Wrangell
- Surveyor Services, Wrangell - Surveying Service
- Swimming, Wrangell
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